Phenomena and Processes

B-Lymphocyte Heavy Chain Gene Rearrangement

Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

7 entry terms
  • B Cell Heavy Chain Gene Rearrangement
  • B Lymphocyte Heavy Chain Gene Rearrangement
  • B-Cell Heavy Chain Gene Rearrangement
  • Gene Rearrangement, B-Lymphocyte, Heavy Chain
  • B Cell Mu Chain Gene Rearrangement
  • B-Lymphocyte Mu Chain Gene Rearrangement
  • B Lymphocyte Mu Chain Gene Rearrangement

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • B Lymphocytes/immunology (1977-1988)
  • DNA/genetics (1977-1988)
  • Genes, Immunoglobulin (1977-1988)
  • Immunoglobulins, Heavy Chain/genetics (1977-1988)

MeSH Hierarchy

Tree Numbers

  1. G05.344.401.501
  2. G12.500.274.501

AMA Style

References

  1. National Library of Medicine. B-Lymphocyte Heavy Chain Gene Rearrangement. Medical Subject Headings (MeSH). 2026. Unique ID D015326. http://id.nlm.nih.gov/mesh/2026/D015326
  2. B-Lymphocyte Heavy Chain Gene Rearrangement. In: Wikidata. https://www.wikidata.org/wiki/Q71130743