Chemicals and Drugs

B-Cell Activating Factor

A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.

MeSH Record

Classification

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MeSH Record

Synonyms

20 entry terms
  • Antigens, CD257
  • B Cell Activating Factor
  • B Lymphocyte Stimulator
  • B-Lymphocyte Activating Factor
  • BAFF Ligand
  • BLyS Protein
  • CD257 Antigen
  • CD257 Antigens
  • TALL-1 Protein
  • THANK Protein
  • TNF Superfamily, Member 13b
  • TNF and APOL-Related Leukocyte Expressed Ligand 1
  • TNFSF13B Protein
  • Tumor Necrosis Factor Ligand Superfamily Member 13b
  • Activating Factor, B-Cell
  • Activating Factor, B-Lymphocyte
  • Antigen, CD257
  • B Lymphocyte Activating Factor
  • TALL 1 Protein
  • TNF and APOL Related Leukocyte Expressed Ligand 1

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1999)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. B-Cell Activating Factor. Medical Subject Headings (MeSH). 2026. Unique ID D053264. http://id.nlm.nih.gov/mesh/2026/D053264
  2. B-Cell Activating Factor. In: Wikipedia. https://en.wikipedia.org/wiki/B-cell_activating_factor
  3. B-Cell Activating Factor. In: Wikidata. https://www.wikidata.org/wiki/Q409346