Structured Summary
Abstract
An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
Chemical Identity
Chemical Information
- Molecular Formula
- C9H7N7O2S
- Molecular Weight
- 277.27 g/mol
- CAS Registry No.
- 446-86-6
- IUPAC Name
- 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
- InChIKey
- LMEKQMALGUDUQG-UHFFFAOYSA-N
- SMILES
- CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
- MeSH Unique ID
- D001379
- Source
- PubChem CID 2265
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- Azothioprine
- Azathioprine Sodium
- Azathioprine Sodium Salt
- Azathioprine Sulfate
- Immuran
- Imuran
- Imurel
- Sodium, Azathioprine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
66(64)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Azathioprine. Medical Subject Headings (MeSH). 2026. Unique ID D001379. http://id.nlm.nih.gov/mesh/2026/D001379
- Azathioprine. In: Wikipedia. https://en.wikipedia.org/wiki/Azathioprine
- Azathioprine. In: Wikidata. https://www.wikidata.org/wiki/Q18939
- Azathioprine. In: PubChem Compound. CID 2265. https://pubchem.ncbi.nlm.nih.gov/compound/2265