Chemicals and Drugs

Avapritinib

A tyrosine kinase receptor inhibitor that targets mutants of PROTO-ONCOGENE PROTEIN KIT and PLATELET-DERIVED GROWTH FACTOR ALPHA RECEPTOR.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A tyrosine kinase receptor inhibitor that targets mutants of PROTO-ONCOGENE PROTEIN KIT and PLATELET-DERIVED GROWTH FACTOR ALPHA RECEPTOR.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • (1S)-1-(4-Fluorophenyl)-1-(2-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo(2,1-f)(1,2,4)triazin-4-yl)-1-piperazinyl)-5-pyrimidinyl)ethanamine
  • 5-Pyrimidinemethanamine, alpha-(4-fluorophenyl)-alpha-methyl-2-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo(2,1-f)(1,2,4)triazin-4-yl)-1-piperazinyl)-, (alphaS)-
  • Ayvakit
  • BLU-285

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2026 (2020)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Avapritinib. Medical Subject Headings (MeSH). 2026. Unique ID D000099289. http://id.nlm.nih.gov/mesh/2026/D000099289