Anatomy

Autophagosomes

Large spherical double-layered structures which function in AUTOPHAGY to engulf intracellular components such as ORGANELLES or pathogens. Their outer membrane then fuses with the LYSOSOME (forming the AUTOLYSOSOME) and the inner membrane and contents are digested by lysosomal HYDROLASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Large spherical double-layered structures which function in AUTOPHAGY to engulf intracellular components such as ORGANELLES or pathogens. Their outer membrane then fuses with the LYSOSOME (forming the AUTOLYSOSOME) and the inner membrane and contents are digested by lysosomal HYDROLASES.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Autophagosome
  • Phagophores
  • Phagophore

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Autophagy (1976-2016)
  • Phagocytosis (1975-2016)
  • Phagosomes (1986-2016)

MeSH Hierarchy

Tree Number

  1. A11w.284w.430w.214w.190.875w.190.700w.500w

AMA Style

References

  1. National Library of Medicine. Autophagosomes. Medical Subject Headings (MeSH). 2026. Unique ID D000071182. http://id.nlm.nih.gov/mesh/2026/D000071182
  2. Autophagosomes. In: Wikipedia. https://en.wikipedia.org/wiki/Autophagosome
  3. Autophagosomes. In: Wikidata. https://www.wikidata.org/wiki/Q14882441