Chemicals and Drugs

Auranofin

An oral chrysotherapeutic agent for the treatment of rheumatoid arthritis. Its exact mechanism of action is unknown, but it is believed to act via immunological mechanisms and alteration of lysosomal enzyme activity. Its efficacy is slightly less than that of injected gold salts, but it is better tolerated, and side effects which occur are potentially less serious.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An oral chrysotherapeutic agent for the treatment of rheumatoid arthritis. Its exact mechanism of action is unknown, but it is believed to act via immunological mechanisms and alteration of lysosomal enzyme activity. Its efficacy is slightly less than that of injected gold salts, but it is better tolerated, and side effects which occur are potentially less serious.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • Crisinor
  • Ridaura
  • Ridauran
  • SK&F D 39162
  • SK&F-39162
  • SK&F 39162
  • SK&F39162

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Gold (1966-1974)
  • Gold Thioglucose/analogs & derivatives (1975-1986)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Auranofin. Medical Subject Headings (MeSH). 2026. Unique ID D001310. http://id.nlm.nih.gov/mesh/2026/D001310
  2. Auranofin. In: Wikipedia. https://en.wikipedia.org/wiki/Auranofin
  3. Auranofin. In: Wikidata. https://www.wikidata.org/wiki/Q421230