Chemicals and Drugs

Atovaquone

A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.

Chemical Identity

Chemical Information

Molecular Formula
C22H19ClO3
Molecular Weight
366.8 g/mol
CAS Registry No.
95233-18-4
IUPAC Name
3-[4-(4-chlorophenyl)cyclohexyl]-4-hydroxynaphthalene-1,2-dione
InChIKey
BSJMWHQBCZFXBR-UHFFFAOYSA-N
SMILES
C1CC(CCC1C2=CC=C(C=C2)Cl)C3=C(C4=CC=CC=C4C(=O)C3=O)O
MeSH Unique ID
D053626
Source
PubChem CID 74989

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • 2-(4-(4'-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone
  • 2-(trans-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone
  • 566C
  • 566C80
  • 566C80 hydroxynaphthoquinone
  • Mepron
  • Wellvone
  • compound 566
  • hydroxynaphthoquinone 566C80
  • hydroxynaphthoquinone, 566C80

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2007(1990)

MeSH Record

Previous Indexing

  • Naphthoquinones (1990-2006)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Atovaquone. Medical Subject Headings (MeSH). 2026. Unique ID D053626. http://id.nlm.nih.gov/mesh/2026/D053626
  2. Atovaquone. In: Wikipedia. https://en.wikipedia.org/wiki/Atovaquone
  3. Atovaquone. In: Wikidata. https://www.wikidata.org/wiki/Q418179
  4. Atovaquone. In: PubChem Compound. CID 74989. https://pubchem.ncbi.nlm.nih.gov/compound/74989