Chemicals and Drugs

Ataxin-7

A component of the STAGA transcription coactivator-HAT complex that functions in Cone Rod Homeobox Protein (CRX)-dependent gene activation. It also stabilizes MICROTUBULES. CAG repeat expansion in the ATXN-7 coding region is associated with the development of SPINOCEREBELLAR ATAXIA 7.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A component of the STAGA transcription coactivator-HAT complex that functions in Cone Rod Homeobox Protein (CRX)-dependent gene activation. It also stabilizes MICROTUBULES. CAG repeat expansion in the ATXN-7 coding region is associated with the development of SPINOCEREBELLAR ATAXIA 7.

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Synonyms

9 entry terms
  • ATXN7 Protein
  • Atxn-7 Protein
  • SCA7 Protein
  • Spinocerebellar Ataxia 7 Protein
  • Ataxin 7
  • Atxn 7 Protein
  • Protein, ATXN7
  • Protein, Atxn-7
  • Protein, SCA7

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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History Note

2016

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Previous Indexing

  • Nerve Tissue Proteins (1997-2015)

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References

  1. National Library of Medicine. Ataxin-7. Medical Subject Headings (MeSH). 2026. Unique ID D000067719. http://id.nlm.nih.gov/mesh/2026/D000067719
  2. Ataxin-7. In: Wikidata. https://www.wikidata.org/wiki/Q41796805