Chemicals and Drugs

Ataxia Telangiectasia Mutated Proteins

A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • A-T Protein
  • AT Mutated Protein
  • ATM Protein
  • A T Protein
  • Mutated Protein, AT
  • Protein, A-T
  • Protein, AT Mutated

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2014

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Ataxia Telangiectasia Mutated Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D064007. http://id.nlm.nih.gov/mesh/2026/D064007
  2. Ataxia Telangiectasia Mutated Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q24773792