Chemicals and Drugs

Aspirin

The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Chemical Identity

Chemical Information

Molecular Formula
C9H8O4
Molecular Weight
180.16 g/mol
CAS Registry No.
50-78-2
IUPAC Name
2-acetyloxybenzoic acid
InChIKey
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
SMILES
CC(=O)OC1=CC=CC=C1C(=O)O
MeSH Unique ID
D001241
Source
PubChem CID 2244

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

18 entry terms
  • 2-(Acetyloxy)benzoic Acid
  • Acetylsalicylic Acid
  • Acid, Acetylsalicylic
  • Acetysal
  • Acylpyrin
  • Aloxiprimum
  • Colfarit
  • Dispril
  • Easprin
  • Ecotrin
  • Endosprin
  • Magnecyl
  • Micristin
  • Polopirin
  • Polopiryna
  • Solprin
  • Solupsan
  • Zorprin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1965; was ACETYLSALICYLIC ACID 1963-1964

MeSH Hierarchy

Tree Number

  1. D02w.455w.426w.559w.389.657w.410.595w.176w

MeSH Record

NLM Classification

QV 95

AMA Style

References

  1. National Library of Medicine. Aspirin. Medical Subject Headings (MeSH). 2026. Unique ID D001241. http://id.nlm.nih.gov/mesh/2026/D001241
  2. Aspirin. In: Wikipedia. https://en.wikipedia.org/wiki/Aspirin
  3. Aspirin. In: Wikidata. https://www.wikidata.org/wiki/Q18216
  4. Aspirin. In: PubChem Compound. CID 2244. https://pubchem.ncbi.nlm.nih.gov/compound/2244