Chemicals and Drugs

Asparaginyl Endopeptidase

A cysteine endopeptidase that occurs in LYSOSOMES of MACROPHAGES where it hydrolyzes molecules containing ASPARAGINE. It plays a critical role in ANTIGEN PRESENTATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cysteine endopeptidase that occurs in LYSOSOMES of MACROPHAGES where it hydrolyzes molecules containing ASPARAGINE. It plays a critical role in ANTIGEN PRESENTATION.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • Asparagine Endopeptidase
  • Asparaginylendopeptidase
  • Delta Secretase
  • Legumain

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1991); use ASPARAGINYLENDOPEPTIDASE (NM) 1991-2025

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.262w.500.102
  2. D08.811w.277w.656w.300w.200.001

AMA Style

References

  1. National Library of Medicine. Asparaginyl Endopeptidase. Medical Subject Headings (MeSH). 2026. Unique ID D000099240. http://id.nlm.nih.gov/mesh/2026/D000099240
  2. Asparaginyl Endopeptidase. In: Wikidata. https://www.wikidata.org/wiki/Q103840877