Anatomy

Artificial Mammalian Chromosomes

DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, that are required for successful replication, propagation to and maintainance in progeny mammalian cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, that are required for successful replication, propagation to and maintainance in progeny mammalian cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

9 entry terms
  • Artificial Chromosomes, Mammalian
  • Chromosomes, Artificial, Mammalian
  • Chromosomes, Mammalian Artificial
  • MAC (Chromosome)
  • MACs (Chromosomes)
  • Mammalian Artificial Chromosomes
  • Artificial Chromosome, Mammalian
  • Chromosome, Mammalian Artificial
  • Mammalian Artificial Chromosome

MeSH Record

Aspects Covered

13 allowable subheadings

Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, physiology, radiation effects, ultrastructure, virology.

MeSH Record

Indexing Annotation

coord with specific animal /genet only if particularly discussed

MeSH Record

History Note

2002(2001)

MeSH Record

Previous Indexing

  • Chromosomes (1994-2000)

MeSH Hierarchy

Tree Numbers

  1. A11w.284w.187w.178.190
  2. A11w.284w.187w.520.190
  3. G05.360w.162w.178.190
  4. G05.360w.162w.520.190
  5. G05.360w.337w.249.190

AMA Style

References

  1. National Library of Medicine. Artificial Mammalian Chromosomes. Medical Subject Headings (MeSH). 2026. Unique ID D022221. http://id.nlm.nih.gov/mesh/2026/D022221
  2. Artificial Mammalian Chromosomes. In: Wikidata. https://www.wikidata.org/wiki/Q70303710