Structured Summary
Abstract
An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence or deficiency of this enzyme causes the metabolic disease CITRULLINEMIA in humans. EC 6.3.4.5.
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Classification
Broader headings
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See Also
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Synonyms
3 entry terms
- Argininosuccinate Synthetase
- Synthase, Argininosuccinate
- Synthetase, Argininosuccinate
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/defic: consider also CITRULLINEMIA
MeSH Record
History Note
98(75)
MeSH Record
Previous Indexing
- Arginine (1973-1974)
- Ligases (1973-1974)
- Succinates (1973-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Argininosuccinate Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D001124. http://id.nlm.nih.gov/mesh/2026/D001124
- Argininosuccinate Synthase. In: Wikipedia. https://en.wikipedia.org/wiki/Argininosuccinate_synthase
- Argininosuccinate Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q24741403