Structured Summary
Abstract
A triphosphate nucleotide analog which is the biologically active form of CYTARABINE. It inhibits nuclear DNA synthesis.
Chemical Identity
Chemical Information
- Molecular Formula
- C9H16N3O14P3
- Molecular Weight
- 483.16 g/mol
- CAS Registry No.
- 13191-15-6
- IUPAC Name
- [[(2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
- InChIKey
- PCDQPRRSZKQHHS-CCXZUQQUSA-N
- SMILES
- C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
- MeSH Unique ID
- D001085
- Source
- PubChem CID 25774
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
9 entry terms
- Ara-CTP
- Arabinosylcytosine Triphosphate
- Cytarabine Triphosphate
- Cytosine Arabinoside Triphosphate
- Ara CTP
- Triphosphate, Arabinofuranosylcytosine
- Triphosphate, Arabinosylcytosine
- Triphosphate, Cytarabine
- Triphosphate, Cytosine Arabinoside
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(79); was see under ARABINONUCLEOTIDES 1979-90
MeSH Record
Previous Indexing
- Cytarabine (1966-1978)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Arabinofuranosylcytosine Triphosphate. Medical Subject Headings (MeSH). 2026. Unique ID D001085. http://id.nlm.nih.gov/mesh/2026/D001085
- Arabinofuranosylcytosine Triphosphate. In: Wikipedia. https://en.wikipedia.org/wiki/Arabinofuranosylcytosine_triphosphate
- Arabinofuranosylcytosine Triphosphate. In: Wikidata. https://www.wikidata.org/wiki/Q4783465
- Arabinofuranosylcytosine Triphosphate. In: PubChem Compound. CID 25774. https://pubchem.ncbi.nlm.nih.gov/compound/25774