Chemicals and Drugs

Aquaporin 2

Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

5 entry terms
  • AQP2 Protein
  • Aquaporin-2
  • Aquaporin-CD
  • Water Channel Of Collecting Duct
  • Aquaporin CD

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.500w.040w.437
  2. D12.776w.543w.550w.450w.730w.040w.437
  3. D12.776w.543w.585w.400w.730w.040w.530

AMA Style

References

  1. National Library of Medicine. Aquaporin 2. Medical Subject Headings (MeSH). 2026. Unique ID D051399. http://id.nlm.nih.gov/mesh/2026/D051399
  2. Aquaporin 2. In: Wikidata. https://www.wikidata.org/wiki/Q26987774