Structured Summary
Abstract
A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
8 entry terms
- Antiangiogenic AK38 Protein
- Apo Lp(a)
- Apolipoprotein (a)
- Apolipoprotein Lp(a)
- Apolipoprotein Lp(a+)
- Apolipoprotein(a)
- Apoprotein (a)
- Protein, Antiangiogenic AK38
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
do not confuse with APOLIPOPROTEINS A, normal structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS)
MeSH Record
History Note
2007 (1986); use APOLIPOPROTEINS A 1988-2006
MeSH Record
Previous Indexing
- Apolipoproteins (1977-1993)
- Apolipoproteins A (1982-2006)
- Apoproteins (1978-2004)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Apoprotein(a). Medical Subject Headings (MeSH). 2026. Unique ID D053241. http://id.nlm.nih.gov/mesh/2026/D053241
- Apoprotein(a). In: Wikidata. https://www.wikidata.org/wiki/Q100930181