Chemicals and Drugs

Apomorphine

A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.

Chemical Identity

Chemical Information

Molecular Formula
C17H17NO2
Molecular Weight
267.32 g/mol
CAS Registry No.
58-00-4
IUPAC Name
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
InChIKey
VMWNQDUVQKEIOC-CYBMUJFWSA-N
SMILES
CN1CCC2=C3[C@H]1CC4=C(C3=CC=C2)C(=C(C=C4)O)O
MeSH Unique ID
D001058
Source
PubChem CID 6005

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Apokinon
  • Apomorphin-Teclapharm
  • Apomorphine Chloride
  • Apomorphine Hydrochloride
  • Apomorphine Hydrochloride Anhydrous
  • Apomorphine Hydrochloride, Anhydrous
  • Apomorphine Hydrochloride, Hemihydrate
  • Britaject
  • Apomorphin Teclapharm

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

APOMORPHINE DERIVATIVES was see under APOMORPHINE 1969-77

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.098.038.290w
  2. D03w.633.100.531.085.030.290w
  3. D03w.633.400.095.290w

AMA Style

References

  1. National Library of Medicine. Apomorphine. Medical Subject Headings (MeSH). 2026. Unique ID D001058. http://id.nlm.nih.gov/mesh/2026/D001058
  2. Apomorphine. In: Wikipedia. https://en.wikipedia.org/wiki/Apomorphine
  3. Apomorphine. In: Wikidata. https://www.wikidata.org/wiki/Q269111
  4. Apomorphine. In: PubChem Compound. CID 6005. https://pubchem.ncbi.nlm.nih.gov/compound/6005