Chemicals and Drugs

Apolipoprotein A-II

The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN A-I from HDL particles and generates a stable HDL complex. ApoA-II can modulate the activation of LECITHIN CHOLESTEROL ACYLTRANSFERASE in the presence of APOLIPOPROTEIN A-I, thus affecting HDL metabolism.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The second most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. It has a high lipid affinity and is known to displace APOLIPOPROTEIN A-I from HDL particles and generates a stable HDL complex. ApoA-II can modulate the activation of LECITHIN CHOLESTEROL ACYLTRANSFERASE in the presence of APOLIPOPROTEIN A-I, thus affecting HDL metabolism.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

21 entry terms
  • Apo A-2
  • Apo A-II
  • Apo A2
  • Apo AII
  • ApoA-2
  • ApoA-II
  • Apolipoprotein A-2
  • Apolipoprotein A2
  • Apolipoprotein AII
  • Apolipoprotein A 2
  • Apolipoprotein A II
  • Apo A-II Isoproteins
  • Apolipoprotein A-II Isoproteins
  • Pro-Apo A-II
  • Pro-Apolipoprotein A-II
  • Proapolipoprotein A-II
  • Apo A II Isoproteins
  • Apolipoprotein A II Isoproteins
  • Pro Apo A II
  • Pro Apolipoprotein A II
  • Proapolipoprotein A II

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

1992 (1978); for PRO-APOLIPOPROTEIN A-II (NM) use APOLIPOPROTEINS A & PROTEIN PRECURSORS 1985-2006; for APOLIPOPROTEIN A-II ISOPROTEINS (NM) use APOLIPOPROTEINS A 1983-2006

MeSH Record

Previous Indexing

  • Apolipoproteins (1977-1984)
  • Apolipoproteins A (1985-1991)

MeSH Hierarchy

Tree Numbers

  1. D10w.532w.091w.200.150w
  2. D12.776w.070.400w.200.150w
  3. D12.776w.521w.120w.200.150w

AMA Style

References

  1. National Library of Medicine. Apolipoprotein A-II. Medical Subject Headings (MeSH). 2026. Unique ID D016633. http://id.nlm.nih.gov/mesh/2026/D016633
  2. Apolipoprotein A-II. In: Wikipedia. https://en.wikipedia.org/wiki/Apolipoprotein_A2
  3. Apolipoprotein A-II. In: Wikidata. https://www.wikidata.org/wiki/Q21154572