Diseases

Apical Hypertrophic Cardiomyopathy

A hypertrophic cardiomyopathy characterized by apical hypertrophy, typically LEFT VENTRICULAR HYPERTROPHY (described as ace of spades sign), and deep T-wave inversions in EKG. Clinical symptoms include minor symptoms such as CHEST PAIN; DYSPNEA; and SYNCOPE to more complex symptoms such as ATRIAL FIBRILLATION; VENTRICULAR FIBRILLATION; MYOCARDIAL INFARCTION and CONGESTIVE HEART FAILURE. A transient left ventricular apical hypertrophy is sometimes associated with TAKOTSUBO CARDIOMYOPATHY.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A hypertrophic cardiomyopathy characterized by apical hypertrophy, typically LEFT VENTRICULAR HYPERTROPHY (described as ace of spades sign), and deep T-wave inversions in EKG. Clinical symptoms include minor symptoms such as CHEST PAIN; DYSPNEA; and SYNCOPE to more complex symptoms such as ATRIAL FIBRILLATION; VENTRICULAR FIBRILLATION; MYOCARDIAL INFARCTION and CONGESTIVE HEART FAILURE. A transient left ventricular apical hypertrophy is sometimes associated with TAKOTSUBO CARDIOMYOPATHY.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • Apical-Variant HCM
  • Apical Hypertrophic Cardiomyopathies
  • Apical Variant HCM
  • Apical-Variant HCMs
  • Cardiomyopathy, Apical Hypertrophic
  • HCM, Apical-Variant
  • Hypertrophic Cardiomyopathy, Apical
  • Left Ventricular Apical Hypertrophic Cardiomyopathy

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2023

MeSH Record

Previous Indexing

  • Cardiomyopathy, Hypertrophic (1980-2022)

MeSH Hierarchy

Tree Numbers

  1. C14w.280w.195w.400w.500
  2. C14w.280w.238w.100w.250

AMA Style

References

  1. National Library of Medicine. Apical Hypertrophic Cardiomyopathy. Medical Subject Headings (MeSH). 2026. Unique ID D000092183. http://id.nlm.nih.gov/mesh/2026/D000092183
  2. Apical Hypertrophic Cardiomyopathy. In: Wikidata. https://www.wikidata.org/wiki/Q116589409