Chemicals and Drugs

Apazone

An anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also has uricosuric properties and has been used to treat gout.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also has uricosuric properties and has been used to treat gout.

Chemical Identity

Chemical Information

Molecular Formula
C16H20N4O2
Molecular Weight
300.36 g/mol
CAS Registry No.
13539-59-8
IUPAC Name
5-(dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione
InChIKey
MPHPHYZQRGLTBO-UHFFFAOYSA-N
SMILES
CCCC1C(=O)N2C3=C(C=CC(=C3)C)N=C(N2C1=O)N(C)C
MeSH Unique ID
D001032
Source
PubChem CID 26098

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione
  • Azapropazone
  • Apazone Dihydrate
  • Prolixan
  • Rheumox
  • Tolyprin
  • Dihydrate, Apazone

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under TRIAZINES 1975-90

MeSH Record

Previous Indexing

  • Dimethylamines (1973-1974)
  • Malonates (1973-1974)
  • Triazines (1971-1974)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 95

AMA Style

References

  1. National Library of Medicine. Apazone. Medical Subject Headings (MeSH). 2026. Unique ID D001032. http://id.nlm.nih.gov/mesh/2026/D001032
  2. Apazone. In: Wikipedia. https://en.wikipedia.org/wiki/Azapropazone
  3. Apazone. In: Wikidata. https://www.wikidata.org/wiki/Q368222
  4. Apazone. In: PubChem Compound. CID 26098. https://pubchem.ncbi.nlm.nih.gov/compound/26098