Chemicals and Drugs

Antisense DNA

DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.

MeSH Record

Classification

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MeSH Record

Synonyms

4 entry terms
  • Anti-Sense DNA
  • DNA, Antisense
  • Anti Sense DNA
  • DNA, Anti-Sense

MeSH Record

Aspects Covered

31 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • DNA (1988-1990)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QU 58.5

AMA Style

References

  1. National Library of Medicine. Antisense DNA. Medical Subject Headings (MeSH). 2026. Unique ID D016373. http://id.nlm.nih.gov/mesh/2026/D016373
  2. Antisense DNA. In: Wikidata. https://www.wikidata.org/wiki/Q50430208