Structured Summary
Abstract
A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
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Synonyms
4 entry terms
- Anoctamin
- TMEM16 Protein Family
- TMEM16 Proteins
- Protein Family, TMEM16
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- Chloride Channels (2009-2017)
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AMA Style
References
- National Library of Medicine. Anoctamins. Medical Subject Headings (MeSH). 2026. Unique ID D000075368. http://id.nlm.nih.gov/mesh/2026/D000075368
- Anoctamins. In: Wikidata. https://www.wikidata.org/wiki/Q24779607