Structured Summary
Abstract
A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
See Also
MeSH Record
Synonyms
11 entry terms
- ACE-Related Carboxypeptidase
- ACE2 Angiotensin-Converting Enzyme Protein 2
- ACE2 Enzyme
- ACE2 Protein
- Angiotensin Converting Enzyme 2
- Angiotensin-Converting Enzyme-Related Carboxypeptidase
- ACE Related Carboxypeptidase
- ACE2 Angiotensin Converting Enzyme Protein 2
- Angiotensin Converting Enzyme Related Carboxypeptidase
- Carboxypeptidase, ACE-Related
- Carboxypeptidase, Angiotensin-Converting Enzyme-Related
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2021 (2000)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Angiotensin-Converting Enzyme 2. Medical Subject Headings (MeSH). 2026. Unique ID D000085962. http://id.nlm.nih.gov/mesh/2026/D000085962
- Angiotensin-Converting Enzyme 2. In: Wikidata. https://www.wikidata.org/wiki/Q301630