Structured Summary
Abstract
An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting.
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Synonyms
1 entry terms
- Angiopoietin 2
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2004; use ANGIOPOIETIN-2 (NM) 1997-2003
MeSH Record
Previous Indexing
- Angiogenesis Factor (2003)
- Proteins (1999-2002)
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AMA Style
References
- National Library of Medicine. Angiopoietin-2. Medical Subject Headings (MeSH). 2026. Unique ID D042702. http://id.nlm.nih.gov/mesh/2026/D042702
- Angiopoietin-2. In: Wikidata. https://www.wikidata.org/wiki/Q24721083