Chemicals and Drugs

Angiopoietin-1

The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Angiopoietin 1

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

see SCR for organism-specific terms

MeSH Record

History Note

2004; use ANGIOPOIETIN-1 (NM) 1997-2003

MeSH Record

Previous Indexing

  • Angiogenesis Factor (2003)
  • Membrane Glycoproteins (1997-2003)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Angiopoietin-1. Medical Subject Headings (MeSH). 2026. Unique ID D042683. http://id.nlm.nih.gov/mesh/2026/D042683
  2. Angiopoietin-1. In: Wikidata. https://www.wikidata.org/wiki/Q24785556