Chemicals and Drugs

Androstenedione

A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.

Chemical Identity

Chemical Information

Molecular Formula
C19H26O2
Molecular Weight
286.4 g/mol
CAS Registry No.
63-05-8
IUPAC Name
(8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
InChIKey
AEMFNILZOJDQLW-QAGGRKNESA-N
SMILES
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C
MeSH Unique ID
D000735
Source
PubChem CID 6128

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

4 entry terms
  • 4-Androstene-3,17-dione
  • delta-4-Androstenedione
  • 4 Androstene 3,17 dione
  • delta 4 Androstenedione

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

74(73)

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.054.079.329w
  2. D04w.210.500w.578.502w.112w
  3. D06.472w.040.502w.112w
  4. D06.472w.334.851w.968.875w

MeSH Record

NLM Classification

WJ 875

AMA Style

References

  1. National Library of Medicine. Androstenedione. Medical Subject Headings (MeSH). 2026. Unique ID D000735. http://id.nlm.nih.gov/mesh/2026/D000735
  2. Androstenedione. In: Wikipedia. https://en.wikipedia.org/wiki/Androstenedione
  3. Androstenedione. In: Wikidata. https://www.wikidata.org/wiki/Q411064
  4. Androstenedione. In: PubChem Compound. CID 6128. https://pubchem.ncbi.nlm.nih.gov/compound/6128