Chemicals and Drugs

Anaphase-Promoting Complex-Cyclosome Apc4 Subunit

A subunit of the anaphase-promoting complex whose primary function is to provide structural support for the catalytic and substrate-recognition modules of the complex. Apc4, along with Apc5, tethers the tetratricopeptide-coactivator binding subcomplex to the main structural subunit, Apc1.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subunit of the anaphase-promoting complex whose primary function is to provide structural support for the catalytic and substrate-recognition modules of the complex. Apc4, along with Apc5, tethers the tetratricopeptide-coactivator binding subcomplex to the main structural subunit, Apc1.

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Classification

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Synonyms

5 entry terms
  • Anapc4
  • Apc4 Subunit, Anaphase-Promoting Complex
  • Apc4 Subunit, Anaphase-Promoting Complex-Cyclosome
  • Apc4 Subunit, Anaphase Promoting Complex
  • Apc4 Subunit, Anaphase Promoting Complex Cyclosome

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2014

MeSH Record

Previous Indexing

  • Cell Cycle Proteins (1996-2003)
  • Ligases (1996-2003)
  • Ubiquitin-Protein Ligase Complexes (2004-2013)

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AMA Style

References

  1. National Library of Medicine. Anaphase-Promoting Complex-Cyclosome Apc4 Subunit. Medical Subject Headings (MeSH). 2026. Unique ID D064192. http://id.nlm.nih.gov/mesh/2026/D064192
  2. Anaphase-Promoting Complex-Cyclosome Apc4 Subunit. In: Wikidata. https://www.wikidata.org/wiki/Q24773783