Structured Summary
Abstract
A highly evolutionarily conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc subunits 6, 7, and 8, have been shown to mediate protein-protein interactions, suggesting that Apc3 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to co-activators and APC-C inhibitors.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
6 entry terms
- Anapc3
- Apc3 Subunit, Anaphase-Promoting Complex
- Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome
- CDC27 Protein
- Apc3 Subunit, Anaphase Promoting Complex
- Apc3 Subunit, Anaphase Promoting Complex Cyclosome
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2014
MeSH Record
Previous Indexing
- Cell Cycle Proteins (1996-2003)
- Ligases (1996-2003)
- Ubiquitin-Protein Ligase Complexes (2004-2013)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Anaphase-Promoting Complex-Cyclosome Apc3 Subunit. Medical Subject Headings (MeSH). 2026. Unique ID D064191. http://id.nlm.nih.gov/mesh/2026/D064191
- Anaphase-Promoting Complex-Cyclosome Apc3 Subunit. In: Wikidata. https://www.wikidata.org/wiki/Q77198333