Structured Summary
Abstract
Together with the Apc2 subunit, forms the catalytic core of the E3 ubiquitin ligase, anaphase-promoting complex-cyclosome. It has a RING H2 domain which interacts with the cullin domain of Apc2. Apc11 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
5 entry terms
- Anapc11
- Apc11 Subunit, Anaphase-Promoting Complex
- Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome
- Apc11 Subunit, Anaphase Promoting Complex
- Apc11 Subunit, Anaphase Promoting Complex Cyclosome
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2014
MeSH Record
Previous Indexing
- Cell Cycle Proteins (1996-2013)
- Ligases (1996-2003)
- Ubiquitin-Protein Ligase Complexes (2004-2013)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Anaphase-Promoting Complex-Cyclosome Apc11 Subunit. Medical Subject Headings (MeSH). 2026. Unique ID D064198. http://id.nlm.nih.gov/mesh/2026/D064198
- Anaphase-Promoting Complex-Cyclosome Apc11 Subunit. In: Wikidata. https://www.wikidata.org/wiki/Q24721379