Structured Summary
Abstract
Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core, and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex.
MeSH Record
Classification
Broader headings
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MeSH Record
Synonyms
4 entry terms
- Anapc10
- Apc10 Subunit, Anaphase-Promoting Complex
- Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome
- Apc10 Subunit, Anaphase Promoting Complex
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2014
MeSH Record
Previous Indexing
- Cell Cycle Proteins (1996-2013)
- Ligases (1996-2003)
- Ubiquitin-Protein Ligase Complexes (2004-2013)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Anaphase-Promoting Complex-Cyclosome Apc10 Subunit. Medical Subject Headings (MeSH). 2026. Unique ID D064197. http://id.nlm.nih.gov/mesh/2026/D064197
- Anaphase-Promoting Complex-Cyclosome Apc10 Subunit. In: Wikidata. https://www.wikidata.org/wiki/Q24774256