Structured Summary
Abstract
An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
Chemical Identity
Chemical Information
- Molecular Formula
- C21H19N3O3S
- Molecular Weight
- 393.5 g/mol
- CAS Registry No.
- 51264-14-3
- IUPAC Name
- N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide
- InChIKey
- XCPGHVQEEXUHNC-UHFFFAOYSA-N
- SMILES
- COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42
- MeSH Unique ID
- D000677
- Source
- PubChem CID 2179
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
25 entry terms
- AMSA
- Cain's Acridine
- m-AMSA
- meta-AMSA
- Cain Acridine
- Cains Acridine
- meta AMSA
- AMSA P-D
- Amsacrina
- Amsidine
- Amsidyl
- NSC-141549
- NSC-156303
- NSC-249992
- SN-11841
- SN11841
- AMSA P D
- AMSA PD
- NSC 141549
- NSC 156303
- NSC 249992
- NSC141549
- NSC156303
- NSC249992
- SN 11841
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
87
MeSH Record
Previous Indexing
- Acridines (1966-1979)
- Aminoacridines (1980-1986)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Amsacrine. Medical Subject Headings (MeSH). 2026. Unique ID D000677. http://id.nlm.nih.gov/mesh/2026/D000677
- Amsacrine. In: Wikipedia. https://en.wikipedia.org/wiki/Amsacrine
- Amsacrine. In: Wikidata. https://www.wikidata.org/wiki/Q2784004
- Amsacrine. In: PubChem Compound. CID 2179. https://pubchem.ncbi.nlm.nih.gov/compound/2179