Chemicals and Drugs

Amrinone

A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.

Chemical Identity

Chemical Information

Molecular Formula
C10H9N3O
Molecular Weight
187.20 g/mol
CAS Registry No.
60719-84-8
IUPAC Name
3-amino-5-pyridin-4-yl-1H-pyridin-2-one
InChIKey
RNLQIBCLLYYYFJ-UHFFFAOYSA-N
SMILES
C1=CN=CC=C1C2=CNC(=O)C(=C2)N
MeSH Unique ID
D000676
Source
PubChem CID 3698

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • 5-Amino-(3,4'-bipyridine)-6(1H)-one
  • Amrinon
  • Cordemcura
  • Inocor
  • Win-40680
  • Wincoram
  • Win 40680
  • Win40680

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Aminopyridines (1979-1986)
  • Pyridines (1966-1978)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Amrinone. Medical Subject Headings (MeSH). 2026. Unique ID D000676. http://id.nlm.nih.gov/mesh/2026/D000676
  2. Amrinone. In: Wikipedia. https://en.wikipedia.org/wiki/Amrinone
  3. Amrinone. In: Wikidata. https://www.wikidata.org/wiki/Q422724
  4. Amrinone. In: PubChem Compound. CID 3698. https://pubchem.ncbi.nlm.nih.gov/compound/3698