Chemicals and Drugs

Amlodipine

A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.

Chemical Identity

Chemical Information

Molecular Formula
C20H25ClN2O5
Molecular Weight
408.9 g/mol
CAS Registry No.
88150-42-9
IUPAC Name
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey
HTIQEAQVCYTUBX-UHFFFAOYSA-N
SMILES
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
MeSH Unique ID
D017311
Source
PubChem CID 2162

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Amlodipine Besylate
  • Amlodipine Maleate
  • Amlodipine Maleate (1:1)
  • Amlodipine, (+-)-Isomer
  • Amlodipine, (+-)-Isomer, Maleate (1:1)
  • Amlodipine, (R)-Isomer
  • Amlodipine, (S)-Isomer, Maleate (1:1)
  • Amlodis
  • Amlor
  • Astudal
  • Istin
  • Norvasc

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

93; was AMLODIPINE (NM) 1986-92

MeSH Record

Previous Indexing

  • Nifedipine/analogs & derivatives (1986-1992)

MeSH Hierarchy

Tree Number

  1. D03w.383.725w.203.065w

AMA Style

References

  1. National Library of Medicine. Amlodipine. Medical Subject Headings (MeSH). 2026. Unique ID D017311. http://id.nlm.nih.gov/mesh/2026/D017311
  2. Amlodipine. In: Wikipedia. https://en.wikipedia.org/wiki/Amlodipine
  3. Amlodipine. In: Wikidata. https://www.wikidata.org/wiki/Q411347
  4. Amlodipine. In: PubChem Compound. CID 2162. https://pubchem.ncbi.nlm.nih.gov/compound/2162