Chemicals and Drugs

Amifostine

A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

24 entry terms
  • APAETP
  • Amifostine Anhydrous
  • Amifostine Disodium Salt
  • Amifostine Monohydrate
  • Amifostine Monohydrochloride
  • Amifostine Trihydrate
  • Aminopropyl Aminoethylthiophosphate
  • Aminopropylaminoethylthiophosphate
  • Aminopropylaminoethylthiophosphoric Acid
  • Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
  • Ethiofos
  • Ethiofos Anhydrous
  • Ethyol
  • Gammaphos
  • NSC-296961
  • S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid
  • WR-2721
  • YM-08310
  • NSC 296961
  • NSC296961
  • WR 2721
  • WR2721
  • YM 08310
  • YM08310

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.

MeSH Record

History Note

1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984

MeSH Record

Previous Indexing

  • Diamines (1974-1976)
  • Organothiophosphorus Compounds (1972-1976)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Amifostine. Medical Subject Headings (MeSH). 2026. Unique ID D004999. http://id.nlm.nih.gov/mesh/2026/D004999
  2. Amifostine. In: Wikipedia. https://en.wikipedia.org/wiki/Amifostine
  3. Amifostine. In: Wikidata. https://www.wikidata.org/wiki/Q251698