Chemicals and Drugs

Amdinocillin Pivoxil

Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.

Chemical Identity

Chemical Information

Molecular Formula
C21H33N3O5S
Molecular Weight
439.6 g/mol
CAS Registry No.
32886-97-8
IUPAC Name
2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
InChIKey
NPGNOVNWUSPMDP-HLLBOEOZSA-N
SMILES
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)N=CN3CCCCCC3)C(=O)OCOC(=O)C(C)(C)C)C
MeSH Unique ID
D000561
Source
PubChem CID 115163

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Mecillinam Pivaloyl Ester
  • Pivamdinocillin
  • Pivmecillinam
  • Pivaloyl Ester, Mecillinam
  • Pivoxil, Amdinocillin
  • FL-1039
  • Pivmecillinam Hydrochloride
  • Selexid
  • FL 1039
  • FL1039
  • Hydrochloride, Pivmecillinam

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(85); was see under AMDINOCILLIN 1985-90; was PIVMECILLINAM see under PENICILLANIC ACIDS 1978-84

MeSH Record

Previous Indexing

  • Antibiotics (1966-1972)
  • Penicillanic Acids (1973-1977)
  • Thiazoles (1966-1977)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.750w.124w.036w
  2. D02w.886w.108w.750w.124w.036w
  3. D03w.633.100.300w.750w.124w.036w

AMA Style

References

  1. National Library of Medicine. Amdinocillin Pivoxil. Medical Subject Headings (MeSH). 2026. Unique ID D000561. http://id.nlm.nih.gov/mesh/2026/D000561
  2. Amdinocillin Pivoxil. In: Wikipedia. https://en.wikipedia.org/wiki/Pivmecillinam
  3. Amdinocillin Pivoxil. In: Wikidata. https://www.wikidata.org/wiki/Q418086
  4. Amdinocillin Pivoxil. In: PubChem Compound. CID 115163. https://pubchem.ncbi.nlm.nih.gov/compound/115163