Structured Summary
Abstract
The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
See Also
MeSH Record
Synonyms
14 entry terms
- Alu Family
- Alu Repetitive Sequences
- Alu Element
- Alu Families
- Alu Repetitive Sequence
- Element, Alu
- Elements, Alu
- Families, Alu
- Family, Alu
- Repetitive Sequence, Alu
- Repetitive Sequences, Alu
- Sequence, Alu Repetitive
- Sequences, Alu Repetitive
- Alu-Like Repetitive Sequence
MeSH Record
Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
MeSH Record
History Note
1999; use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-1998; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-1998
MeSH Record
Previous Indexing
- Repetitive Sequences, Nucleic Acid (1981-1998)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Alu Elements. Medical Subject Headings (MeSH). 2026. Unique ID D020087. http://id.nlm.nih.gov/mesh/2026/D020087
- Alu Elements. In: Wikipedia. https://en.wikipedia.org/wiki/Alu_element
- Alu Elements. In: Wikidata. https://www.wikidata.org/wiki/Q412199