Chemicals and Drugs

Alphaprodine

An opioid analgesic chemically related to and with an action resembling that of MEPERIDINE, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An opioid analgesic chemically related to and with an action resembling that of MEPERIDINE, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067)

Chemical Identity

Chemical Information

Molecular Formula
C16H23NO2
Molecular Weight
261.36 g/mol
IUPAC Name
[(3R,4S)-1,3-dimethyl-4-phenylpiperidin-4-yl] propanoate
InChIKey
UVAZQQHAVMNMHE-CJNGLKHVSA-N
SMILES
CCC(=O)O[C@]1(CCN(C[C@H]1C)C)C2=CC=CC=C2
MeSH Unique ID
D000522
Source
PubChem CID 204163

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Alphaprodine Hydrochloride
  • Nisentil
  • Prodine
  • Hydrochloride, Alphaprodine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

65(64)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Alphaprodine. Medical Subject Headings (MeSH). 2026. Unique ID D000522. http://id.nlm.nih.gov/mesh/2026/D000522
  2. Alphaprodine. In: Wikidata. https://www.wikidata.org/wiki/Q5666520
  3. Alphaprodine. In: PubChem Compound. CID 204163. https://pubchem.ncbi.nlm.nih.gov/compound/204163