Chemicals and Drugs

Aldosterone

A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

Chemical Identity

Chemical Information

Molecular Formula
C21H28O5
Molecular Weight
360.4 g/mol
CAS Registry No.
52-39-1
IUPAC Name
(8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-13-carbaldehyde
InChIKey
PQSUYGKTWSAVDQ-ZVIOFETBSA-N
SMILES
C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C=O)O
MeSH Unique ID
D000450
Source
PubChem CID 5839

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

See Also

MeSH Record

Synonyms

2 entry terms
  • Aldosterone, (+-)-Isomer
  • Aldosterone, (11 beta,17 alpha)-Isomer

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/defic: consider also HYPOALDOSTERONISM; consider also RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM see RENIN-ANGIOTENSIN SYSTEM & do not index under ALDOSTERONE unless particularly discussed

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.745.745w.654w.062w
  2. D06.472w.040.585w.353.118w

AMA Style

References

  1. National Library of Medicine. Aldosterone. Medical Subject Headings (MeSH). 2026. Unique ID D000450. http://id.nlm.nih.gov/mesh/2026/D000450
  2. Aldosterone. In: Wikipedia. https://en.wikipedia.org/wiki/Aldosterone
  3. Aldosterone. In: Wikidata. https://www.wikidata.org/wiki/Q184564
  4. Aldosterone. In: PubChem Compound. CID 5839. https://pubchem.ncbi.nlm.nih.gov/compound/5839