Chemicals and Drugs

Ajmaline

An alkaloid found in the root of RAUWOLFIA SERPENTINA, among other plant sources. It is a class 1-A antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alkaloid found in the root of RAUWOLFIA SERPENTINA, among other plant sources. It is a class 1-A antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.

Chemical Identity

Chemical Information

Molecular Formula
C20H26N2O2
Molecular Weight
326.4 g/mol
CAS Registry No.
4360-12-7
IUPAC Name
(1R,9R,10S,12R,13S,14R,16S,18R)-13-ethyl-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-triene-14,18-diol
InChIKey
CJDRUOGAGYHKKD-HEFSZTOGSA-N
SMILES
CC[C@H]1[C@@H]2C[C@H]3[C@H]4[C@@]5(C[C@@H](C2[C@H]5O)N3[C@@H]1O)C6=CC=CC=C6N4C
MeSH Unique ID
D000404
Source
PubChem CID 441080

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Ajmaline Hydrochloride
  • Aritmina
  • Cardiorythmine
  • Gilurtymal
  • Rauverid
  • Serenol
  • Tachmalin
  • Wolfina

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

73(71)

MeSH Record

Previous Indexing

  • Rauwolfia (1966-1970)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.436w.681.077w
  2. D03w.633.100.473.402w.681.077w
  3. D03w.633.100.496.500.500w.681.077w

AMA Style

References

  1. National Library of Medicine. Ajmaline. Medical Subject Headings (MeSH). 2026. Unique ID D000404. http://id.nlm.nih.gov/mesh/2026/D000404
  2. Ajmaline. In: Wikipedia. https://en.wikipedia.org/wiki/Ajmaline
  3. Ajmaline. In: Wikidata. https://www.wikidata.org/wiki/Q385858
  4. Ajmaline. In: PubChem Compound. CID 441080. https://pubchem.ncbi.nlm.nih.gov/compound/441080