Structured Summary
Abstract
A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.
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Classification
Broader headings
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Synonyms
8 entry terms
- B Cell Progenitor Kinase
- Bruton's Tyrosine Kinase
- Bruton Tyrosine Kinase
- Brutons Tyrosine Kinase
- Kinase, Agammaglobulinaemia Tyrosine
- Kinase, Bruton's Tyrosine
- Tyrosine Kinase, Agammaglobulinaemia
- Tyrosine Kinase, Bruton's
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2019 (1993)
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AMA Style
References
- National Library of Medicine. Agammaglobulinaemia Tyrosine Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D000077329. http://id.nlm.nih.gov/mesh/2026/D000077329
- Agammaglobulinaemia Tyrosine Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Bruton%27s_tyrosine_kinase
- Agammaglobulinaemia Tyrosine Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q423572