Chemicals and Drugs

Adenylosuccinate Synthase

A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyzes the synthesis of adenylosuccinate from GTP; IMP; and aspartate with the formation of orthophosphate and GDP. EC 6.3.4.4.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyzes the synthesis of adenylosuccinate from GTP; IMP; and aspartate with the formation of orthophosphate and GDP. EC 6.3.4.4.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

6 entry terms
  • Adenylosuccinate Synthetase
  • Succino-AMP Synthetase
  • Succino AMP Synthetase
  • Synthase, Adenylosuccinate
  • Synthetase, Adenylosuccinate
  • Synthetase, Succino-AMP

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

98(79)

MeSH Record

Previous Indexing

  • Aspartic Acid (1966-1978)
  • Inosine Monophosphate (1975-1978)
  • Inosine Nucleotides (1971-1978)
  • Ligases (1966-1978)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Adenylosuccinate Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D000265. http://id.nlm.nih.gov/mesh/2026/D000265
  2. Adenylosuccinate Synthase. In: Wikipedia. https://en.wikipedia.org/wiki/Adenylosuccinate_synthase
  3. Adenylosuccinate Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q24777607