Diseases

Addison Disease

An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

14 entry terms
  • Addison's Disease
  • Primary Adrenal Insufficiency
  • Primary Adrenocortical Insufficiency
  • Primary Hypoadrenalism
  • Addisons Disease
  • Adrenal Insufficiency, Primary
  • Adrenocortical Insufficiencies, Primary
  • Adrenocortical Insufficiency, Primary
  • Disease, Addison
  • Hypoadrenalism, Primary
  • Hypoadrenalisms, Primary
  • Insufficiencies, Primary Adrenocortical
  • Insufficiency, Primary Adrenocortical
  • Primary Adrenocortical Insufficiencies

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2005 (1963)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

WK 765

AMA Style

References

  1. National Library of Medicine. Addison Disease. Medical Subject Headings (MeSH). 2026. Unique ID D000224. http://id.nlm.nih.gov/mesh/2026/D000224
  2. Addison Disease. In: Wikipedia. https://en.wikipedia.org/wiki/Addison%27s_disease
  3. Addison Disease. In: Wikidata. https://www.wikidata.org/wiki/Q8282