Structured Summary
Abstract
A naphthalene derivative that has specificity for RETINOIC ACID RECEPTORS. It is used as a DERMATOLOGIC AGENT for the treatment of ACNE.
Chemical Identity
Chemical Information
- Molecular Formula
- C28H28O3
- Molecular Weight
- 412.5 g/mol
- CAS Registry No.
- 106685-40-9
- IUPAC Name
- 6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid
- InChIKey
- LZCDAPDGXCYOEH-UHFFFAOYSA-N
- SMILES
- COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5
- MeSH Unique ID
- D000068816
- Source
- PubChem CID 60164
MeSH Record
Classification
Broader headings
Narrower headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- 6-(3-(1-adamantyl)-4-methoxyphenyl)-2-naphthoic acid
- Adaferin
- Differin
- Differine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2016 (1990)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Adapalene. Medical Subject Headings (MeSH). 2026. Unique ID D000068816. http://id.nlm.nih.gov/mesh/2026/D000068816
- Adapalene. In: Wikipedia. https://en.wikipedia.org/wiki/Adapalene
- Adapalene. In: Wikidata. https://www.wikidata.org/wiki/Q352348
- Adapalene. In: PubChem Compound. CID 60164. https://pubchem.ncbi.nlm.nih.gov/compound/60164