Diseases

Acquired Hyperostosis Syndrome

Syndrome consisting of SYNOVITIS; ACNE CONGLOBATA; PALMOPLANTAR PUSTULOSIS; HYPEROSTOSIS; and OSTEITIS. The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Syndrome consisting of SYNOVITIS; ACNE CONGLOBATA; PALMOPLANTAR PUSTULOSIS; HYPEROSTOSIS; and OSTEITIS. The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.

MeSH Record

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MeSH Record

Synonyms

10 entry terms
  • SAPHO Syndrome
  • Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis
  • Acquired Hyperostosis Syndromes
  • Hyperostosis Syndrome, Acquired
  • Hyperostosis Syndromes, Acquired
  • SAPHO Syndromes
  • Syndrome, Acquired Hyperostosis
  • Syndrome, SAPHO
  • Syndromes, Acquired Hyperostosis
  • Syndromes, SAPHO

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1999

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AMA Style

References

  1. National Library of Medicine. Acquired Hyperostosis Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D020083. http://id.nlm.nih.gov/mesh/2026/D020083
  2. Acquired Hyperostosis Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/SAPHO_syndrome
  3. Acquired Hyperostosis Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q1515163