Structured Summary
Abstract
A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.
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Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2009(1982); use GALACTOSYLGALACTOSYLGLUCOSYLCERAMIDASE 1983-2008
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Previous Indexing
- Galactosylgalactosylglucosylceramidase (1974-2008)
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References
- National Library of Medicine. Acid Ceramidase. Medical Subject Headings (MeSH). 2026. Unique ID D055573. http://id.nlm.nih.gov/mesh/2026/D055573
- Acid Ceramidase. In: Wikidata. https://www.wikidata.org/wiki/Q21173179