Chemicals and Drugs

Acebutolol

A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.

Chemical Identity

Chemical Information

Molecular Formula
C18H28N2O4
Molecular Weight
336.4 g/mol
CAS Registry No.
37517-30-9
IUPAC Name
N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide
InChIKey
GOEMGAFJFRBGGG-UHFFFAOYSA-N
SMILES
CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C
MeSH Unique ID
D000070
Source
PubChem CID 1978

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

17 entry terms
  • Acetobutolol
  • Acebutolol Hydrochloride
  • Apo-Acebutolol
  • M & B 17803A
  • M&B-17803 A
  • Monitan
  • Neptal
  • Novo-Acebutolol
  • Prent
  • Rhotral
  • Sectral
  • Apo Acebutolol
  • ApoAcebutolol
  • M&B 17803 A
  • M&B17803 A
  • Novo Acebutolol
  • NovoAcebutolol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

75

MeSH Record

Previous Indexing

  • Anilides (1974)
  • Ethanolamines (1974)
  • Phenyl Ethers (1974)
  • Propylamines (1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.033w.100w.624w.698.025w
  2. D02w.033w.755.624w.698.025w
  3. D02w.092w.063w.624w.698.025w

AMA Style

References

  1. National Library of Medicine. Acebutolol. Medical Subject Headings (MeSH). 2026. Unique ID D000070. http://id.nlm.nih.gov/mesh/2026/D000070
  2. Acebutolol. In: Wikipedia. https://en.wikipedia.org/wiki/Acebutolol
  3. Acebutolol. In: Wikidata. https://www.wikidata.org/wiki/Q418857
  4. Acebutolol. In: PubChem Compound. CID 1978. https://pubchem.ncbi.nlm.nih.gov/compound/1978