Chemicals and Drugs

Acarbose

An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An inhibitor of ALPHA-GLUCOSIDASES that retards the digestion and absorption of DIETARY CARBOHYDRATES in the SMALL INTESTINE.

Chemical Identity

Chemical Information

Molecular Formula
C25H43NO18
Molecular Weight
645.6 g/mol
IUPAC Name
(2R,3R,4R,5S,6R)-5-[(2R,3R,4R,5S,6R)-5-[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol
InChIKey
XUFXOAAUWZOOIT-SXARVLRPSA-N
SMILES
C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO
MeSH Unique ID
D020909
Source
PubChem CID 444254

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Bay g 5421
  • Glucobay
  • Glucor
  • Glumida
  • Prandase
  • Precose

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2000; use ACARBOSE (NM) 1979-1999

MeSH Record

Previous Indexing

  • Cyclohexanols (1979-1981)
  • Polysaccharides, Bacterial (1978-1979)
  • Trisaccharides (1980-1999)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

WK 825

AMA Style

References

  1. National Library of Medicine. Acarbose. Medical Subject Headings (MeSH). 2026. Unique ID D020909. http://id.nlm.nih.gov/mesh/2026/D020909
  2. Acarbose. In: Wikipedia. https://en.wikipedia.org/wiki/Acarbose
  3. Acarbose. In: Wikidata. https://www.wikidata.org/wiki/Q338005
  4. Acarbose. In: PubChem Compound. CID 444254. https://pubchem.ncbi.nlm.nih.gov/compound/444254