Structured Summary
Abstract
A carbocyclic nucleoside reverse transcriptase inhibitor with potent and selective anti-HIV activity.
Chemical Identity
Chemical Information
- Molecular Formula
- C14H18N6O
- Molecular Weight
- 286.33 g/mol
- CAS Registry No.
- 136470-78-5
- IUPAC Name
- [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol
- InChIKey
- MCGSCOLBFJQGHM-SCZZXKLOSA-N
- SMILES
- C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO
- MeSH Unique ID
- D000099227
- Source
- PubChem CID 441300
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
35 entry terms
- (-)-cis-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol
- (1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol
- Avacavir
- ((1R,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-cyclopent-2-enyl)methanol
- ((1R,4S)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methanol
- (+)-Abacavir
- (+)-Abacavir Sulfate
- (+-)-Abacavir Sulfate
- (1R,4R)-Abacavir
- (1R,4S)-Abacavir Sulfate
- (1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopentene-1-methanol succinate (1:1) (salt)
- 1592U89
- 2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1R,4S)-, sulfate (2:1)
- 2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1S,4R)-, rel-, sulfate (2:1)
- 2-cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, hydrochloride, hydrate (1:1:1), (1S,4R)-
- Abacavir Hydrochloride Monohydrate
- Abacavir Succinate
- Abacavir Sulfate
- Abacavir Sulfate Racemic
- Abacavir Sulfate, (+)-
- Abacavir Sulfate, (+-)-
- Abacavir Sulfate, (1R,4S)-
- Abacavir Sulphate
- Abacavir enantiomer
- Abacavir, (1R,4S)-
- Abacavir, Trans-, (+-)-
- Abacavir, trans-
- Abamune
- DRG 0257
- DRG-0257
- DRG0257
- Ziagen
- abacavir, (+)-
- trans-Abacavir
- trans-Abacavir R,R-
MeSH Record
Aspects Covered
24 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2026 (1997)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Abacavir. Medical Subject Headings (MeSH). 2026. Unique ID D000099227. http://id.nlm.nih.gov/mesh/2026/D000099227
- Abacavir. In: Wikipedia. https://en.wikipedia.org/wiki/Abacavir
- Abacavir. In: Wikidata. https://www.wikidata.org/wiki/Q304330
- Abacavir. In: PubChem Compound. CID 441300. https://pubchem.ncbi.nlm.nih.gov/compound/441300