Structured Summary
Abstract
An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
13 entry terms
- ATP Citrate (pro-3S)-Lyase
- ATP Citrate Lyase
- ATP Citrate Synthase
- ATP-Dependent Citrate Lyase
- Citrate Cleavage Enzyme
- ATP Dependent Citrate Lyase
- Citrate Lyase, ATP
- Citrate Lyase, ATP-Dependent
- Citrate Synthase, ATP
- Cleavage Enzyme, Citrate
- Lyase, ATP Citrate
- Lyase, ATP-Dependent Citrate
- Synthase, ATP Citrate
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
98(73)
MeSH Record
Previous Indexing
- Lyases (1966-1972)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. ATP Citrate (pro-S)-Lyase. Medical Subject Headings (MeSH). 2026. Unique ID D001275. http://id.nlm.nih.gov/mesh/2026/D001275
- ATP Citrate (pro-S)-Lyase. In: Wikidata. https://www.wikidata.org/wiki/Q21096258