Diseases

AIDS-Related Complex

A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.

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Classification

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Synonyms

7 entry terms
  • ARC
  • Lymphadenopathy Syndrome
  • AIDS Related Complex
  • Complex, AIDS-Related
  • Lymphadenopathy Syndromes
  • Syndrome, Lymphadenopathy
  • Syndromes, Lymphadenopathy

MeSH Record

Aspects Covered

36 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, transmission, urine, veterinary, virology.

MeSH Record

Indexing Annotation

coordinate with HIV-1 or HIV-2 if pertinent

MeSH Record

History Note

87

MeSH Record

Previous Indexing

  • Acquired Immunodeficiency Syndrome (1983-1986)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. AIDS-Related Complex. Medical Subject Headings (MeSH). 2026. Unique ID D000386. http://id.nlm.nih.gov/mesh/2026/D000386
  2. AIDS-Related Complex. In: Wikipedia. https://en.wikipedia.org/wiki/AIDS-related_complex
  3. AIDS-Related Complex. In: Wikidata. https://www.wikidata.org/wiki/Q4651855